Towards a digital human “behaviorome”

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MultiMed Engineers carried out research activities aimed to investigate the application of Data Analytics technology to the capture, analysis and interpretation of human behavior as a determinant of health. The expectation is that such effort would conduct to the definition of a digital human behaviorome that could greatly improve clinical research, by providing more informative features on people health conditions, linked to a modifiable determinant that can be used for improving health policies.

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HTA for oncology prognostic models

Cattura2MultiMed Engineers further applied its expertise in conducting HTA studies with the MAFEIP Tool, addressing the oncology domain. The health and economic effects of using the BD2Decide prognostic models in comparison with usual TNM staging, have been evaluated on the basis of the Project’s dataset, which includes several hundreds of Head & Neck Cancer cases. Four treatment escalation and de-escalation scenarios have been analysed.

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HTA shows City4Age approach as viable

 

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MultiMed Engineers conducted a Health Technology Assessment for evaluating the frailty prevention scheme based on the City4Age Project’s early detection system. The results show that City4Age dominates the current standard of care from the Healthcare point of view, and exhibits a very cost-effective ICER of 3,380 €/QALY from the Societal perspective, allowing to conclude that the City4Age approach is viable.

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Detecting frailty through smart-city datasets

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Thanks to the availablity of experimental datasets from the City4Age Athens PilotMultiMed Engineers investigated how Machine Learning algorithms can be leveraged to early detect frailty onset in aging citizens, living in smart-cities.

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Chat-bot development

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MultiMed Engineers is experimenting the application of chat-bot technology to several business cases, including a NLP-based query language for a CRM database, and a conversational application to support a business-to-business “classifieds” system.

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MultiMed Engineers, in cooperation with Università di Pavia, has presentend the City4Age Project to the European Geriatricians which were attending the EuGMS Congress 2017 held in Nice (France) on September 20-22, 2017.
The Project was presented as an extended abstract plus an oral presentation.
In additon, the City4Age Team attending the Conference was invited to take part at the founding workshop of the EUGMS’s Special Interest Group on Gerontechnology, in order to provide relevant insights and expertise.

Link to abstract book…

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In cooperation with Università di Pavia and Università del SalentoMultiMed Engineers has coauthored a paper titled Data driven MCI and frailty prevention: geriatric modelling in the City4Age project, presented at IEEE 3° International Forum on Research and Technologies for Society and Industry (RTSI 2017) held in Modena (Italy) on 11-13 September 2017. The paper presents the computational model, developed by MultiMed Engineers, Università di Pavia and Università del Salento, that drives early detection of aging conditions through unobtrusive collection of smart-city datasets.

Link to paper abstract…

City4Age frailty and MCI risk model

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MultiMed Engineers, with the support of Università di Pavia (Department of Internal Medicine and Therapeutics), has drafted the first version of the City4Age frailty and MCI risk model.  This document, which is a public deliverable of the City4Age Project (D2.1), presents the selection of geriatrics indicators that are currently being used to elaborate the behavioural markers for MCI and frailty, envisaged by the Project.

Download the executive summary…

IEEE Second International Smart Cities Conference

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In cooperation with Politecnico di Milano, MultiMed Engineers has coauthored a paper presented at theIEEE Second International Smart Cities Conference (ISC2 2016), held in Trento (Italy) on 12-15 September 2016. The paper, which is titled City4Age: Smart Cities for Health Prevention, discusses how data from smart cities and ad-hoc sensors can be harnessed for the prevention of Mild Cognitive Impairment (MCI) and frailty in aged people.

Link to paper abstract…

China’s CRISPR twins might have had their brains inadvertently enhanced

The brains of two genetically edited girls born in China last year may have been changed in ways that enhance cognition and memory, scientists say. The twins, called Lulu and Nana, reportedly had their genes modified before birth by a Chinese scientific team using the new editing tool CRISPR. The goal was to make the girls…

Source: China’s CRISPR twins might have had their brains inadvertently enhanced

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